Whole Genome arrays:

The objective of developing a primer set to amplify fragments of genomic DNA encompassing the entire euchromatic genome or a clone tiling path to meet the same goal, is enthusiastically supported by many groups. Such a resource is highly desirable for both chromatin IP, DNA binding, and transcriptional profiling studies.  

 

Experimental genome tiling arrays have been produced by Affymetrix and are being used by The Berkeley Drosophila Transcription Network Project http://bdtnp.lbl.gov/ .  K. White in Yale has produced a Nimblegen tiling array http://genome.med.yale.edu/FEEP/FEEP.html and several other groups have generated pilot amplicon tiling arrays (K. White-Yale, FlyChip- Cambridge, G. Cavalli – Montpellier; http://www.igh.cnrs.fr/equip/cavalli/index.html ).

 

More recently a collaboration between K. White (Yale), S. Russell (Cambridge) and G. Micklem (Cambridge) has begun to generate a complete tiling array the entire unique portion of the Drosophila euchromatic genome.  Once generated primers and slides will be available from FlyChip and DGRC.